Description

4-Phenyl-n-(4,4,6-Trimethyl-1H-Pyrimidin-2-Yl)Quinazolin-2-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of heterocyclic compounds. This compound is critical for the research and development of novel therapeutic agents, particularly in oncology and targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential kinase inhibitors and other targeted cancer therapies.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Research: Acts as a reference standard or a probe molecule in biochemical assays to study enzyme inhibition and cellular pathways.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create more complex, functionalized quinazoline derivatives for various applications.

Basic Information

Product Name	4-Phenyl-n-(4,4,6-Trimethyl-1H-Pyrimidin-2-Yl)Quinazolin-2-Amine
CAS No.	511514-03-7
Molecular Formula	C27H25N5
Molecular Weight	419.52 g/mol
Synonyms	4-Phenyl-N-(4,4,6-trimethyl-1H-pyrimidin-2-yl)quinazolin-2-amine; 2-Quinazolinamine, 4-phenyl-N-(4,4,6-trimethyl-1H-pyrimidin-2-yl)-; 511514-03-7; Quinazolin-2-amine, 4-phenyl-N-(4,4,6-trimethyl-1H-pyrimidin-2-yl)-; 4-Phenyl-N-(4,4,6-trimethyl-2-pyrimidinyl)-2-quinazolinamine
EINECS	Contact for details

Quality Control

Our 4-Phenyl-n-(4,4,6-Trimethyl-1H-Pyrimidin-2-Yl)Quinazolin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.