Description

2-Imino-N,10-Dimethyl-5-Oxo-1-(3-Pyridinylmethyl)-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidine-3-Carboxamide is a high-purity, complex heterocyclic compound with significant potential in advanced pharmaceutical research and development. This molecule serves as a critical pharmacological intermediate or reference standard for the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and inflammatory disease research.
• Kinase Inhibitor Research: Serves as a core scaffold or precursor for the development of potent and selective kinase inhibitors due to its fused pyrimidine-pyridine structure.
• Biochemical Tool Compound: Used in high-throughput screening (HTS) and in vitro assays to study specific biological pathways and target validation.
• Reference Standard: Provides an essential analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies to optimize the potency and pharmacokinetic properties of lead compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.

Basic Information

Product Name	2-Imino-N,10-Dimethyl-5-Oxo-1-(3-Pyridinylmethyl)-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidine-3-Carboxamide
CAS No.	510761-48-5
Molecular Formula	C21H18N6O2
Molecular Weight	386.41 g/mol
Synonyms	1-(3-Pyridinylmethyl)-2-imino-N,10-dimethyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide; Dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide, 1,5-dihydro-2-imino-N,10-dimethyl-5-oxo-1-(3-pyridinylmethyl)-; GSK-3 Inhibitor XV (common research alias); CAS 510761-48-5
EINECS	Contact for details

Quality Control

Our 2-Imino-N,10-Dimethyl-5-Oxo-1-(3-Pyridinylmethyl)-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidine-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity analysis, NMR and MS confirmation, and residual solvent screening, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.