Description

5-Bromoquinoline-8-Carbonitrile is a versatile brominated quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated and nitrile-substituted structure makes it a valuable building block for constructing complex heterocyclic systems and functionalized molecules. This high-purity compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active quinoline-based compounds.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the quinoline scaffold for bioactive molecule design.
• Material Science: Building block for creating organic semiconductors, liquid crystals, and photoactive materials due to its electron-deficient aromatic system.
• Chemical Synthesis: Serves as a versatile substrate for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and functional group transformations in medicinal and process chemistry.
• Ligand and Catalyst Development: Used to synthesize novel nitrogen-containing ligands for transition metal catalysis.

Basic Information

Product Name	5-Bromoquinoline-8-Carbonitrile
CAS No.	507476-70-2
Molecular Formula	C10H5BrN2
Molecular Weight	233.07 g/mol
Synonyms	8-Cyano-5-bromoquinoline; 5-Bromo-8-cyanoquinoline; Quinoline, 5-bromo-8-cyano-; 5-Bromoquinoline-8-carbonitrile; 5-Bromo-8-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 5-Bromoquinoline-8-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates, with quality verified by advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.