Description

(-)-2,3-Bis[(2R,5R)-2,5-Dimethylphospholanyl]Maleic Anhydride(1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate is a high-purity, chiral organometallic complex designed for advanced asymmetric synthesis. This compound matters as a highly selective and efficient catalyst for enantioselective hydrogenation and other transition metal-catalyzed reactions, enabling the production of optically pure intermediates. It is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Fine Chemical Synthesis: Enabling the production of chiral building blocks and specialty chemicals with high optical purity.
• Pharmaceutical R&D: Critical for developing new active pharmaceutical ingredients (APIs) and investigating novel synthetic pathways.
• Methodology Development: Used in academic and industrial research to explore new catalytic cycles and ligand-metal combinations.
• Process Chemistry: Scaling up enantioselective transformations from laboratory to pilot plant and manufacturing scales.

Basic Information

Item	Details
Product Name	(-)-2,3-Bis[(2R,5R)-2,5-Dimethylphospholanyl]Maleic Anhydride(1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate
CAS No.	507224-99-9
Molecular Formula	C₂₄H₃₈BF₄O₃P₂Rh
Molecular Weight	632.20 g/mol
Synonyms	(-)-2,3-Bis[(2R,5R)-2,5-Dimethylphospholano]maleic Anhydride(1,5-Cyclooctadiene)Rhodium(I) Tetrafluoroborate; Rhodium(I) (1,5-cyclooctadiene)((2R,5R)-2,5-dimethylphospholano)maleic anhydride tetrafluoroborate; (R,R)-Me-DuPhos-Rh Catalyst; (R,R)-2,3-Bis(2,5-dimethylphospholanyl)maleic anhydride (1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; DuPhos-Rh Catalyst; Chiral Rhodium(I) Complex; Asymmetric Hydrogenation Catalyst 507224-99-9
EINECS	Contact for details

Quality Control

Our (-)-2,3-Bis[(2R,5R)-2,5-Dimethylphospholanyl]Maleic Anhydride(1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure identity, purity, and catalytic performance. Certificates of Analysis (COA) documenting all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dry, cool place. This material is moisture-sensitive and easily oxidized; prolonged exposure to air, light, or ambient humidity should be avoided to maintain catalytic activity and purity.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Rhodium Content	Contact for details
Solubility	Soluble in dichloromethane, tetrahydrofuran; slightly soluble in toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.