Description

2-(4-Trifluoromethyl-Phenyl)-Quinoline is a high-purity, specialized heterocyclic compound that serves as a critical building block in advanced chemical synthesis. This compound matters for its unique structural features, combining a quinoline core with a trifluoromethylphenyl group, which are highly sought after for modulating the physicochemical properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and as a key intermediate in the synthesis of more complex active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the synthesis of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science: Serves as a precursor for organic light-emitting diodes (OLEDs) and other electronic materials due to its conjugated quinoline structure.
• Ligand Synthesis: Employed in the development of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: Utilized as a core structure for creating sensitive fluorescent markers and sensors in analytical chemistry.
• Academic & Industrial R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	2-(4-Trifluoromethyl-Phenyl)-Quinoline
CAS No.	506421-62-1
Molecular Formula	C₁₆H₁₀F₃N
Molecular Weight	273.25 g/mol
Synonyms	2-[4-(Trifluoromethyl)phenyl]quinoline; 4-(2-Quinolinyl)benzotrifluoride; Quinoline, 2-[4-(trifluoromethyl)phenyl]-; 2-(4-Trifluoromethylphenyl)quinoline; 2-(4-(Trifluoromethyl)phenyl)quinoline; 2-(p-Trifluoromethylphenyl)quinoline
EINECS	Contact for details

Quality Control

Our 2-(4-Trifluoromethyl-Phenyl)-Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and industrial use. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.