Description

5H-Furo[3,4-B]Pyran-5-One, 2,3,7,7A-Tetrahydro-3-Hydroxy-7-Methyl-2-(1E)-1-Propenyl-, (2R,3R,7S,7Ar)- (9Ci) CAS NO 505081-54-9 is a high-purity, stereochemically defined organic compound belonging to the furopyranone class. This molecule is valued as a critical chiral building block and advanced intermediate in sophisticated organic syntheses, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and synthesis of novel active pharmaceutical ingredients (APIs), especially for complex heterocyclic targets.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides where its specific stereochemistry can influence biological activity.
• Fine Chemical Synthesis: Acts as a versatile precursor for synthesizing specialty chemicals, flavors, fragrances, and other high-value compounds requiring precise stereocontrol.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in asymmetric synthesis and natural product total synthesis.
• Process Chemistry Development: Utilized for scaling up synthetic routes from laboratory to pilot plant scale, requiring consistent quality and purity.
• Ligand and Catalyst Development: Potential use as a backbone for creating novel chiral ligands or organocatalysts used in enantioselective transformations.

Basic Information

Product Name	5H-Furo[3,4-B]Pyran-5-One, 2,3,7,7A-Tetrahydro-3-Hydroxy-7-Methyl-2-(1E)-1-Propenyl-, (2R,3R,7S,7Ar)- (9Ci)
CAS No.	505081-54-9
Molecular Formula	C11H14O4
Molecular Weight	210.23 g/mol
Synonyms	(2R,3R,7S,7aR)-2-[(1E)-1-Propen-1-yl]-3-hydroxy-7-methyl-2,3,7,7a-tetrahydro-5H-furo[3,4-b]pyran-5-one; (2R,3R,7S,7aR)-2-[(E)-1-Propenyl]-3-hydroxy-7-methyl-2,3,7,7a-tetrahydro-5H-furo[3,4-b]pyran-5-one; 5H-Furo[3,4-b]pyran-5-one, 2,3,7,7a-tetrahydro-3-hydroxy-7-methyl-2-[(1E)-1-propen-1-yl]-, (2R,3R,7S,7aR)-; CAS 505081-54-9; Furopyranone derivative; Chiral furopyranone intermediate.
EINECS	Contact for details

Quality Control

Our 5H-Furo[3,4-B]Pyran-5-One derivative is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity (enantiomeric excess), to ensure it meets the exacting standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.