Description

Quinoline, 5-Fluoro-6-Methyl- (9Ci) CAS NO 503538-41-8 is a high-purity, fluorinated quinoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which introduces both fluorine and methyl substituents onto the quinoline core, enabling precise modulation of electronic and steric properties in target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-infectives, and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Employed in the synthesis of organic semiconductors, light-emitting diodes (OLEDs), and other functional organic materials due to the electron-deficient quinoline scaffold.
• Chemical Biology & Probe Development: Serves as a fluorescent tag or a core structure for designing molecular probes and sensors used in biochemical assays and diagnostic research.
• Academic & Industrial R&D: A versatile reagent for method development and exploration of novel fluorination chemistry and heterocyclic compound libraries.

Basic Information

Product Name	Quinoline, 5-Fluoro-6-Methyl- (9Ci)
CAS No.	503538-41-8
Molecular Formula	C10H8FN
Molecular Weight	161.18 g/mol
Synonyms	5-Fluoro-6-methylquinoline; 6-Methyl-5-fluoroquinoline; 5-Fluoro-6-methyl-quinoline; Quinoline, 5-fluoro-6-methyl-; 5-Fluoro-6-methyl-1-azanaphthalene
EINECS	Contact for details

Quality Control

Our Quinoline, 5-Fluoro-6-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.