Description

4-Chloro-6-(Trifluoromethoxy)-2-(Trifluoromethyl)Quinoline is a high-value, multi-functional heterocyclic building block distinguished by its unique halogenated and trifluoromethoxy substituents. This compound is critical for advanced research and development, offering significant potential to modulate the biological activity, metabolic stability, and lipophilicity of target molecules. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, including potential candidates for drug discovery and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Serves as a crucial precursor for developing next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances bioactivity and environmental stability.
• Material Science Research: Used in the development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient quinoline core.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, leveraging the nitrogen atom for metal coordination.
• Fluorinated Compound Library: An essential building block for constructing diverse libraries of fluorinated compounds for high-throughput screening in drug and agrochemical discovery.

Basic Information

Product Name	4-Chloro-6-(Trifluoromethoxy)-2-(Trifluoromethyl)Quinoline
CAS No.	503148-24-1
Molecular Formula	C11H4ClF6NO
Molecular Weight	315.60 g/mol
Synonyms	4-Chloro-6-(trifluoromethoxy)-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-4-chloro-6-(trifluoromethoxy)quinoline; 4-Chloro-6-trifluoromethoxy-2-trifluoromethylquinoline; Quinoline, 4-chloro-6-(trifluoromethoxy)-2-(trifluoromethyl)-; 503148-24-1
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(Trifluoromethoxy)-2-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be sensitive to strong bases and fluorides; keep away from incompatible materials. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.