Description

8-Methoxy-4-(Trifluoromethyl)Quinolin-2(1H)-One is a high-value, multi-functional heterocyclic building block, distinguished by its methoxy and trifluoromethyl substituents which impart unique electronic and steric properties. This compound is critical for research and development in advanced organic synthesis, particularly for creating novel molecules with enhanced biological activity and material characteristics. It is primarily sought after by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and anti-infective research programs.
• Agrochemical Synthesis: Used in the creation of advanced active ingredients for crop protection, leveraging the stability and bioactivity of the quinolinone core.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLEDs or charge-transport layers, due to its conjugated structure.
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent tags or molecular probes for studying biological systems.
• Academic & Industrial R&D: A versatile building block for method development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Product Name	8-Methoxy-4-(Trifluoromethyl)Quinolin-2(1H)-One
CAS No.	503147-99-7
Molecular Formula	C₁₁H₈F₃NO₂
Molecular Weight	243.18 g/mol
Synonyms	8-Methoxy-4-(trifluoromethyl)-2(1H)-quinolinone; 8-Methoxy-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one; 2-Hydroxy-8-methoxy-4-(trifluoromethyl)quinoline; 503147-99-7; 8-Methoxy-4-trifluoromethyl-2-quinolone
EINECS	Contact for details

Quality Control

Our production of 8-Methoxy-4-(Trifluoromethyl)Quinolin-2(1H)-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for your critical R&D and scale-up processes. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.