Description

Grela 2Nd Generation is an advanced pharmaceutical intermediate or active ingredient, identified by CAS NO 502964-52-5. This compound is critical for the synthesis of next-generation therapeutic agents, offering enhanced efficacy and selectivity in targeted applications. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of innovative drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs).
• Bioconjugation Reagent: Used in the development of antibody-drug conjugates (ADCs) and other targeted therapies.
• Proteolysis-Targeting Chimera (PROTAC) Development: Serves as a critical linker or warhead component in PROTAC molecules for targeted protein degradation.
• Preclinical & Clinical Research: Essential for drug discovery programs in academic, government, and industrial R&D laboratories.
• Chemical Biology Tool: Employed in studies to understand and modulate specific biological pathways and protein functions.

Basic Information

Product Name	Grela 2Nd Generation
CAS No.	502964-52-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Grela-2; Grela Second Generation; Grela Degrader; 502964-52-5; Grela-based PROTAC; Grela Analog; Grela Derivative; Grela Intermediate
EINECS	Contact for details

Quality Control

Our Grela 2Nd Generation is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) and handle it in a moisture-controlled environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.