Description

(1S,4R)-7-tert-Butyl 2-Ethyl 3-Bromo-7-Azabicyclo[2.2.1]Hepta-2,5-Diene-2,7-Dicarboxylate is a high-value, stereochemically defined bicyclic intermediate featuring a reactive bromine substituent. This compound is critical for the synthesis of complex, nitrogen-containing molecular architectures, offering precise control over stereochemistry in advanced pharmaceutical and agrochemical research. It is primarily utilized by process chemists and R&D scientists in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of novel, high-efficacy pesticides and herbicides with specific stereochemical requirements.
• Catalyst & Ligand Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & Industrial R&D: Employed in methodological studies and the exploration of new carbon-nitrogen bond-forming reactions.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals and advanced materials requiring specific bicyclic frameworks.

Basic Information

Product Name	(1S,4R)-7-tert-Butyl 2-Ethyl 3-Bromo-7-Azabicyclo[2.2.1]Hepta-2,5-Diene-2,7-Dicarboxylate
CAS No.	502506-71-0
Molecular Formula	C15H20BrNO4
Molecular Weight	358.23 g/mol
Synonyms	tert-Butyl 2-ethyl 3-bromo-7-azabicyclo[2.2.1]hepta-2,5-diene-2,7-dicarboxylate, (1S,4R)-; 7-Azabicyclo[2.2.1]hepta-2,5-diene-2,7-dicarboxylic acid, 3-bromo-, 1,1-dimethylethyl 2-ethyl ester, (1S,4R)-; 3-Bromo-7-azabicyclo[2.2.1]hepta-2,5-diene-2,7-dicarboxylic acid 7-tert-butyl 2-ethyl ester; Bicyclic bromo-diene ester; Azabicycloheptadiene bromoester
EINECS	Contact for details

Quality Control

Our (1S,4R)-7-tert-Butyl 2-Ethyl 3-Bromo-7-Azabicyclo[2.2.1]Hepta-2,5-Diene-2,7-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.