Description

2-Chloro-4-Fluoro-6-Nitrotoluene is a versatile halogenated nitroaromatic compound that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This intermediate is essential for researchers and manufacturers requiring a high-purity, reliable starting material for constructing active pharmaceutical ingredients (APIs) and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides, leveraging the fluorine and nitro functional groups.
• Dye and Pigment Manufacturing: Serves as a precursor for specialized colorants and functional dyes due to its nitroaromatic structure.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating complex biaryl structures.
• Nucleophilic Aromatic Substitution: The activated nitro and halogen groups make it suitable for reactions with various nucleophiles to introduce new functionalities.

Basic Information

Product Name	2-Chloro-4-Fluoro-6-Nitrotoluene
CAS No.	502496-35-7
Molecular Formula	C7H5ClFNO2
Molecular Weight	189.57 g/mol
Synonyms	1-Chloro-3-fluoro-5-methyl-2-nitrobenzene; 2-Chloro-4-fluoro-6-nitrotoluene; 3-Fluoro-5-methyl-2-nitrochlorobenzene; Toluene, 2-chloro-4-fluoro-6-nitro-; 2-Nitro-4-fluoro-6-chlorotoluene; 6-Chloro-2-fluoro-4-nitrotoluene
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-6-Nitrotoluene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.