Description

2-Bromo-4-Fluoro-6-Nitrotoluene is a halogenated nitroaromatic compound that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This intermediate is essential for researchers and manufacturers in fine chemical, pharmaceutical R&D, and material science industries seeking to introduce specific bromo, fluoro, and nitro functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring halogen and nitro group manipulation.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and pesticides where its specific halogenated structure contributes to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Dye and Pigment Manufacturing: Intermediate for synthesizing complex organic dyes and pigments, leveraging the nitro and halogen substituents.
• Liquid Crystal and OLED Materials: Building block for creating electron-transport or emissive layers in electronic display technologies.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination for constructing biaryl systems.

Basic Information

Product Name	2-Bromo-4-Fluoro-6-Nitrotoluene
CAS No.	502496-33-5
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.03 g/mol
Synonyms	1-Bromo-3-fluoro-5-methyl-2-nitrobenzene; 2-Bromo-4-fluoro-6-nitrotoluene; Toluene, 2-bromo-4-fluoro-6-nitro-; 3-Fluoro-5-methyl-2-nitro-1-bromobenzene; 2-Nitro-4-fluoro-6-bromotoluene; 6-Bromo-2-fluoro-4-nitrotoluene; Benzene, 1-bromo-3-fluoro-5-methyl-2-nitro-
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoro-6-Nitrotoluene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.