Description

(5-Bromo-2-Fluoro-Phenyl)-Hydrazine Hydrochloride is a high-purity aromatic hydrazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized phenyl ring system that enables the construction of complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new molecular entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the bromo and fluoro substituents for bioactivity.
• Heterocyclic Chemistry: Fundamental reagent for constructing indoles, pyrazoles, and other nitrogen-containing heterocycles via cyclization and condensation reactions.
• Material Science Research: Employed in the development of organic semiconductors, ligands for catalysis, and functional polymers.
• Chemical Biology & Proteomics: Acts as a derivatization agent or a handle for bioconjugation in probe and linker molecule synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	(5-Bromo-2-Fluoro-Phenyl)-Hydrazine Hydrochloride
CAS No.	502496-24-4
Molecular Formula	C6H5BrClFN2
Molecular Weight	239.47 g/mol
Synonyms	1-(5-Bromo-2-fluorophenyl)hydrazine hydrochloride; (5-Bromo-2-fluorophenyl)hydrazine HCl; 2-Fluoro-5-bromophenylhydrazine hydrochloride; 5-Bromo-2-fluoro-phenylhydrazine hydrochloride; Hydrazine, (5-bromo-2-fluorophenyl)-, hydrochloride; 1-Hydrazino-5-bromo-2-fluorobenzene hydrochloride
EINECS	Contact for details

Quality Control

Our (5-Bromo-2-Fluoro-Phenyl)-Hydrazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) documenting full specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.