Description

4-Fluoro-2-(trifluoromethyl)phenylhydrazine hydrochloride is a specialized fluorinated phenylhydrazine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which combines fluorine atoms and a hydrazine moiety to enable the construction of complex heterocycles and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to introduce key pharmacophores and modulate the biological activity of target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its ability to modify electronic properties.
• Chemical Biology & Proteomics: Acts as a reactive handle in bioconjugation chemistry for labeling proteins and other biomolecules.
• Dye & Pigment Manufacturing: Serves as a starting material for synthesizing specialized fluorinated dyes with unique light-fastness and color properties.

Basic Information

Product Name	4-Fluoro-2-(Trifluoromethyl)Phenylhydrazine(Hcl)
CAS No.	502496-21-1
Molecular Formula	C7H5F4N2•HCl
Molecular Weight	232.58 g/mol
Synonyms	4-Fluoro-2-(trifluoromethyl)phenylhydrazine hydrochloride; 1-(4-Fluoro-2-(trifluoromethyl)phenyl)hydrazine hydrochloride; 4-Fluoro-α,α,α-trifluoro-o-tolylhydrazine hydrochloride; (4-Fluoro-2-trifluoromethylphenyl)hydrazine HCl; 2-Trifluoromethyl-4-fluorophenylhydrazine hydrochloride; Hydrazine, [4-fluoro-2-(trifluoromethyl)phenyl]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(trifluoromethyl)phenylhydrazine hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.