Description

4-Quinolinol, 3,6,8-Trichloro-2-(Trichloromethyl)- is a highly functionalized quinoline derivative, a specialized organic intermediate of significant interest in advanced chemical synthesis. Its complex halogenated structure makes it a valuable precursor for constructing sophisticated molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce unique steric and electronic properties into target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of novel drug candidates, especially those targeting infectious diseases or cancer, due to the quinoline core's bioactive potential.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, or pesticides, where the chlorinated quinoline structure can impart specific biological activity.
• Ligand Synthesis: Acts as a precursor for creating complex chelating ligands used in catalysis or metal-organic frameworks (MOFs).
• Material Science: Employed in the research of organic electronic materials, such as semiconductors or light-emitting compounds, where its structure can influence charge transport properties.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized, high-performance colorants and pigments for niche applications.
• Cross-Coupling Reactions: The halogen atoms present on the quinoline ring make it a suitable substrate for various palladium-catalyzed cross-coupling reactions to create complex biaryl systems.

Basic Information

Product Name	4-Quinolinol, 3,6,8-Trichloro-2-(Trichloromethyl)-
CAS No.	502143-12-6
Molecular Formula	C10H4Cl6NO
Molecular Weight	380.77 g/mol
Synonyms	3,6,8-Trichloro-2-(trichloromethyl)quinolin-4-ol; 2-(Trichloromethyl)-3,6,8-trichloro-4-quinolinol; 4-Hydroxy-3,6,8-trichloro-2-(trichloromethyl)quinoline; 3,6,8-Trichloro-2-(trichloromethyl)-4-hydroxyquinoline; 4-Quinolinol, 3,6,8-trichloro-2-(trichloromethyl)-; Halogenated Quinoline Derivative
EINECS	Contact for details

Quality Control

Every batch of 4-Quinolinol, 3,6,8-Trichloro-2-(Trichloromethyl)- is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee full traceability and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.