Description

1-Fluoro-2-Iodonaphthalene is a high-purity, halogenated naphthalene derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for applications in cross-coupling reactions and the development of novel functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring fluorinated or iodinated aromatic systems.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the naphthalene core provides biological activity.
• Material Science: Building block for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced electronic materials due to its halogenated aromatic structure.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki, Stille, and Negishi cross-coupling reactions to form biaryl and other complex structures.
• Chemical Synthesis: Valuable reagent for introducing fluorine and iodine functional groups into target molecules in medicinal and synthetic chemistry.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis.

Basic Information

Product Name	1-Fluoro-2-Iodonaphthalene
CAS No.	501433-09-6
Molecular Formula	C₁₀H₆FI
Molecular Weight	272.06 g/mol
Synonyms	2-Iodo-1-fluoronaphthalene; 1-Fluoro-2-iodonaphthalene; Naphthalene, 1-fluoro-2-iodo-; 1-Fluoronaphthalene-2-iodide; 2-Fluoro-1-iodonaphthalene (isomer); 1-F-2-I-Naphthalene; F-INaph
EINECS	Contact for details

Quality Control

Our 1-Fluoro-2-Iodonaphthalene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.