Description

2,5-Dibromo-3-Iodobenzoic Acid is a halogenated benzoic acid derivative that serves as a versatile and highly functionalized synthetic building block. Its value lies in the strategic placement of three different halogens (bromine and iodine) on the aromatic ring, which provides distinct reactivity for selective cross-coupling reactions and further derivatization. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring halogenated aromatic cores for bioactivity or as handles for further functionalization.
• Agrochemical Synthesis: Used in research and development of novel herbicides, fungicides, and insecticides where the halogen atoms contribute to binding affinity and metabolic stability.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers, liquid crystals, or organic electronic materials with unique properties.
• Cross-Coupling Reactions: The iodine and bromine atoms offer orthogonal reactivity for sequential Suzuki, Stille, or Sonogashira coupling reactions to construct complex biaryl structures.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags, where the halogens can be used for radioiodination or as sites for bioconjugation.
• Organic Synthesis Research: A valuable reagent for method development and exploring new reaction pathways in academic and industrial R&D laboratories.

Basic Information

Item	Details
Product Name	2,5-Dibromo-3-Iodobenzoic Acid
CAS No.	501009-11-6
Molecular Formula	C7H3Br2IO2
Molecular Weight	420.81 g/mol
Synonyms	3-Iodo-2,5-dibromobenzoic Acid; Benzoic acid, 2,5-dibromo-3-iodo-; 2,5-Dibromo-3-iodobenzoic acid; 501009-11-6; AI3-28633; AKOS005259052; BRN 3630107; CS-W009767; SCHEMBL1550621; DB-042322; FT-0658087; I14-19117
EINECS	Contact for details

Quality Control

Our 2,5-Dibromo-3-Iodobenzoic Acid is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.