Description

8-Chloro-2-Phenylquinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive carbonyl chloride group and halogenated quinoline core. This compound matters for its role as a critical building block in the synthesis of complex organic molecules, enabling the introduction of the quinoline pharmacophore. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by specialty chemical manufacturers for advanced material science applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for anti-malarial, anti-cancer, and kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinoline structure.
• Material Science Research: Serves as a monomer or cross-linking agent in the creation of advanced polymers, ligands, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized quinoline-based dyes and colorants.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and fluorescent markers for biochemical research.
• Catalyst and Ligand Development: Employed to create novel metal-organic complexes and catalytic systems.

Basic Information

Product Name	8-Chloro-2-Phenylquinoline-4-Carbonyl Chloride
CAS No.	500775-82-6
Molecular Formula	C₁₇H₉Cl₂NO
Molecular Weight	326.17 g/mol
Synonyms	8-Chloro-2-phenylquinoline-4-carbonyl chloride; 8-Chloro-2-phenyl-4-quinolinecarbonyl chloride; 2-Phenyl-8-chloroquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 8-chloro-2-phenyl-; 500775-82-6; 8-Chloro-2-phenylquinoline-4-carboxylic acid chloride; 8-Chloro-2-phenyl-4-quinolinecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-Phenylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity, and is supplied with a comprehensive Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support our clients in pharmaceutical development and other regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.