Description

3-Morpholinemethanol,5-(1-Methylethyl)-,(3R,5S)-(9Ci) is a chiral morpholine derivative, a high-value intermediate characterized by its stereochemically defined structure. This compound is crucial for the synthesis of complex molecules where precise spatial orientation is essential for biological activity or material properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use in creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting the central nervous system or metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where the specific stereochemistry can influence efficacy and environmental profile.
• Catalyst Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized, high-purity chemical products requiring a defined morpholine scaffold.
• Academic & Industrial Research: A valuable reagent for methodological development in organic synthesis and medicinal chemistry programs within R&D laboratories.

Basic Information

Product Name	3-Morpholinemethanol,5-(1-Methylethyl)-,(3R,5S)-(9Ci)
CAS No.	500708-43-0
Molecular Formula	C8H17NO2
Molecular Weight	159.23 g/mol
Synonyms	(3R,5S)-5-Isopropyl-3-morpholinemethanol; (3R,5S)-5-(1-Methylethyl)-3-morpholinemethanol; (3R,5S)-5-Isopropylmorpholine-3-methanol; 3-Morpholinemethanol, 5-(1-methylethyl)-, (3R,5S)-; (3R,5S)-5-Isopropyl-3-hydroxymethylmorpholine; trans-5-Isopropyl-3-morpholinemethanol; Chiral Morpholine Alcohol Derivative
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical purity, and identity. We operate under a cGMP-compliant quality management system, and specifications can be tailored to meet the rigorous demands of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.