Description

4-[6-Iodo-2-[(E)-2-(3-Methylphenyl)Ethenyl]-4-Oxoquinazolin-3-Yl]Benzoic Acid is a high-purity, synthetic organic compound belonging to the quinazolinone class, serving as a critical advanced pharmaceutical intermediate. Its complex molecular architecture, featuring an iodinated quinazolinone core linked to a benzoic acid moiety via an ethenyl bridge, makes it a valuable building block for targeted drug discovery and development. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in oncology and inflammation research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential kinase inhibitors and other targeted small-molecule drugs.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies in drug discovery programs.
• Biochemical Tool Compound: May be employed in vitro to study specific biological pathways and protein interactions.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis: Utilized in advanced synthetic organic chemistry for constructing complex heterocyclic systems.

Basic Information

Product Name	4-[6-Iodo-2-[(E)-2-(3-Methylphenyl)Ethenyl]-4-Oxoquinazolin-3-Yl]Benzoic Acid
CAS No.	500273-31-4
Molecular Formula	C24H17IN2O3
Molecular Weight	508.31 g/mol
Synonyms	4-(6-Iodo-2-[(E)-2-(3-methylphenyl)ethenyl]-4-oxo-3(4H)-quinazolinyl)benzoic acid; 4-[6-Iodo-2-[(E)-2-(m-tolyl)vinyl]-4-oxoquinazolin-3-yl]benzoic acid; 3-(4-Carboxyphenyl)-6-iodo-2-[(E)-2-(3-methylphenyl)ethenyl]-4(3H)-quinazolinone; Benzoic acid, 4-[6-iodo-2-[(E)-2-(3-methylphenyl)ethenyl]-4-oxo-3(4H)-quinazolinyl]-; 500273-31-4
EINECS	Contact for details

Quality Control

Our 4-[6-Iodo-2-[(E)-2-(3-Methylphenyl)Ethenyl]-4-Oxoquinazolin-3-Yl]Benzoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and elemental analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.