Description

10-Methyl-6-Aza-Spiro[4.5]Decan-9-One is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic amine-ketone structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Building Block: Used in scaffold hopping and structure-activity relationship (SAR) studies to explore novel chemical space.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides with specific biological activity.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and discovery chemistry projects.
• Ligand and Catalyst Development: Potential use in creating novel chiral ligands or organocatalysts due to its constrained spirocyclic framework.

Basic Information

Product Name	10-Methyl-6-Aza-Spiro[4.5]Decan-9-One
CAS No.	500023-99-4
Molecular Formula	C10H17NO
Molecular Weight	167.25 g/mol
Synonyms	10-Methyl-6-azaspiro[4.5]decan-9-one; 6-Aza-10-methylspiro[4.5]decan-9-one; 9H-6-Aza-10-methylspiro[4.5]decan-9-one; Spiro[4.5]decan-9-one, 10-methyl-6-aza-; 500023-99-4; 10-Methyl-6-aza-spiro[4.5]decan-9-one; 6-Azaspiro[4.5]decan-9-one, 10-methyl-
EINECS	Contact for details

Quality Control

Our 10-Methyl-6-Aza-Spiro[4.5]Decan-9-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications in cGMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.