Description

7,8-Dihydroxy-7,8,9,10-Tetrahydrobenzo(A)Pyrene is a key dihydrodiol metabolite and synthetic intermediate of benzo[a]pyrene, a well-studied polycyclic aromatic hydrocarbon (PAH). This compound is of significant value in environmental and biochemical research for studying metabolic activation pathways and DNA adduct formation. It serves as a critical reference standard and building block for researchers and manufacturers in analytical chemistry, toxicology, and pharmaceutical development.

Application

• Biochemical Research: Used as a metabolite standard in studies investigating the metabolic activation of benzo[a]pyrene and its carcinogenic mechanisms.
• Analytical Reference Standard: Essential for the calibration of analytical equipment (HPLC, GC-MS, LC-MS) in environmental monitoring and food safety testing for PAH contamination.
• Toxicology Studies: Employed in in vitro and in vivo studies to assess genotoxicity, cytotoxicity, and the formation of specific DNA adducts.
• Organic Synthesis: Serves as a sophisticated synthetic intermediate for the preparation of other labeled or modified PAH derivatives for advanced research.
• Environmental Analysis: A crucial component in method development and validation for detecting and quantifying PAH metabolites in biological and environmental samples.

Basic Information

Product Name	7,8-Dihydroxy-7,8,9,10-Tetrahydrobenzo(A)Pyrene
CAS No.	59963-01-8
Molecular Formula	C₂₀H₁₆O₂
Molecular Weight	288.34 g/mol
Synonyms	7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene; Benzo[a]pyrene-7,8-dihydrodiol; BP-7,8-diol; 7,8-Dihydroxy-7,8-dihydrobenzo(a)pyrene; (+/-)-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene; trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene; B[a]P-7,8-diol; 7,8-Dihydrobenzo[a]pyrene-7,8-diol
EINECS	Contact for details

Quality Control

Our 7,8-Dihydroxy-7,8,9,10-Tetrahydrobenzo(A)Pyrene is produced and handled under strict quality protocols to ensure high purity and batch-to-batch consistency, essential for research integrity. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and chromatographic data. We adhere to relevant industry standards for high-purity reference materials and synthetic intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light tan solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.