Description

L-Fucose-(5,6-3H) is a high-specific-activity, tritium-labeled derivative of the deoxy sugar L-fucose. This radiolabeled compound is an essential tool for metabolic and biochemical tracer studies, enabling precise tracking and quantification of fucose incorporation and metabolism in biological systems. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and life science sectors for advanced research into glycobiology, cell surface labeling, and diagnostic assay development.

Application

• Metabolic Tracer Studies: Used to investigate the biosynthesis and metabolic pathways of fucose-containing glycoproteins and glycolipids.
• Glycobiology Research: Essential for studying fucosylation processes, cell-cell recognition, and immune response mechanisms.
• Radioimmunoassays (RIA) & Binding Assays: Serves as a critical labeled ligand in the development and validation of sensitive diagnostic and research assays.
• Pharmacokinetics & Drug Metabolism Studies: Employed to trace the absorption, distribution, metabolism, and excretion (ADME) of fucose-related compounds.
• Cell Surface Labeling: Utilized for fluorescent or autoradiographic labeling of cell surface glycoconjugates for microscopy and flow cytometry.
• Enzyme Activity Assays: Acts as a substrate for fucosyltransferases and other enzymes in activity and inhibition studies.

Basic Information

Product Name	L-Fucose-(5,6-3H)
CAS No.	59892-90-9
Molecular Formula	C6H12O5 (³H labeled)
Molecular Weight	~166.16 g/mol (unlabeled)
Synonyms	6-Deoxy-L-galactose-(5,6-³H); (5,6-³H)-L-Fucose; L(-)-Fucose-(5,6-³H); Tritiated L-Fucose; L-Galacto-6-deoxyhexose-(5,6-³H); 6-Deoxy-L-galactose, tritium labeled; L-Fucose, [5,6-³H]-
EINECS	Contact for details

Quality Control

Every batch of L-Fucose-(5,6-3H) is manufactured and analyzed under strict quality systems to ensure exceptional purity and specific activity. Our products undergo rigorous quality testing, including radiochemical purity analysis by HPLC, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing specific activity, purity, solvent, and concentration is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in the original solvent as supplied. Due to its highly volatile nature (tritium label) and light-sensitive properties, appropriate laboratory containment and handling procedures for radioactive materials must be followed at all times.

Specification

Item	Specification
Appearance	Clear, colorless solution
Identification (HPLC)	Conforms to reference standard
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	10-60 Ci/mmol (Contact for exact value)
Concentration	1 mCi/mL (in ethanol:water solution)
Solvent	Ethanol:Water (9:1 v/v)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.