Description

2-Chloroquinazolin-4-Amine is a versatile and high-value heterocyclic building block, essential for advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel pharmaceuticals and agrochemicals due to its reactive chloroquinazoline core. It is primarily utilized by the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs), crop protection agents, and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Fine Chemical Production: Serves as a versatile building block for creating complex molecules in research and custom synthesis.
• Material Science Research: Investigated for the development of organic semiconductors, ligands for catalysis, and fluorescent dyes.
• Academic & R&D: Employed in medicinal chemistry and organic synthesis laboratories for method development and novel compound library generation.

Basic Information

Product Name	2-Chloroquinazolin-4-Amine
CAS No.	59870-43-8
Molecular Formula	C8H6ClN3
Molecular Weight	179.61 g/mol
Synonyms	4-Amino-2-chloroquinazoline; 2-Chloro-4-aminoquinazoline; 2-Chloro-4-quinazolinamine; 4-Quinazolinamine, 2-chloro-; 2-Chlor-4-chinazolinamin (German); 2-Chloro-4-quinazolylamine; 2-Chloro-4-aminokinazoline; 2-Cl-4-NH2-Quinazoline
EINECS	Contact for details

Quality Control

Our 2-Chloroquinazolin-4-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters. We adhere to cGMP principles for pharmaceutical-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.