Description

(R)-5-Hexadecanolide Standard For GC is a high-purity chiral chemical reference standard, specifically the (R)-enantiomer of the macrolide 5-hexadecanolide. This compound is critically important for analytical method development, validation, and quality control in laboratories requiring precise enantiomeric identification and quantification. It is primarily needed by analytical chemists, quality assurance professionals, and researchers in the pharmaceutical, fragrance, flavor, and fine chemical industries for use as a calibrant in gas chromatography (GC) and other chromatographic techniques.

Application

• Primary Standard for Gas Chromatography (GC): Used as a high-purity calibrant and reference material for method development, system suitability testing, and quantitative analysis.
• Chiral Analysis and Separation: Serves as a critical standard for developing and validating chiral GC or HPLC methods to distinguish between enantiomers of lactones and related compounds.
• Pharmaceutical Research: Employed in the analysis of chiral drug intermediates or active pharmaceutical ingredients (APIs) where stereochemical purity is essential.
• Fragrance and Flavor Industry: Acts as a reference standard for the quality control of macrocyclic lactones, which are key components in musk fragrances and certain flavoring agents.
• Academic and Industrial R&D: Utilized in synthetic chemistry research, metabolic studies, and as a building block or analytical marker in stereoselective synthesis.
• Regulatory Compliance and Testing: Supports testing protocols to meet regulatory requirements for enantiomeric purity in various industrial sectors.

Basic Information

Item	Details
Product Name	(R)-5-Hexadecanolide Standard For GC
CAS No.	59812-96-3
Molecular Formula	C₁₆H₃₀O₂
Molecular Weight	254.41 g/mol
Synonyms	(R)-5-Hexadecanolide; (R)-Hexadecan-5-olide; (R)-ω-6-Hexadecenlactone; (R)-Ambrettolide; (5R)-Oxacyclohexadecan-2-one; (R)-16-Hydroxy-5-hexadecenoic acid lactone; (R)-Cyclohexadeca-5-olide
EINECS	Contact for details

Quality Control

Our (R)-5-Hexadecanolide Standard For GC is manufactured and handled under strict quality management protocols to ensure the highest levels of enantiomeric purity and chemical integrity. Each batch is thoroughly characterized using advanced analytical techniques, including chiral chromatography, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, and related substance data is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability and prevent any potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Enantiomeric Purity (Chiral GC/HPLC)	≥ 99.0% ee (R)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.