Description

n-2,4-Dnp-Dl-Norleucine CAS NO 31356-36-2 is a high-purity chemical derivative of norleucine, specifically modified with a 2,4-dinitrophenyl (DNP) group. This compound is a critical reagent and analytical standard in advanced biochemical research and pharmaceutical development. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical companies engaged in amino acid analysis, protein sequencing, and method development for chromatography.

Application

• Amino Acid Analysis Standard: Serves as a key reference standard in chromatographic methods (HPLC, LC-MS) for the identification and quantification of amino acids and their derivatives.
• Biochemical Research Reagent: Used in studies of protein structure, function, and metabolism, particularly in investigations involving amino acid side-chain modification and labeling.
• Pharmaceutical Intermediate: Acts as a specialized building block or precursor in the synthesis of novel peptide-based compounds and active pharmaceutical ingredients (APIs).
• Proteomics and Metabolomics: Employed in mass spectrometry-based workflows for biomarker discovery and metabolic pathway analysis.
• Quality Control Testing: Used in analytical laboratories for method validation, system suitability testing, and ensuring the accuracy of amino acid profiling in complex samples.

Basic Information

Product Name	n-2,4-Dnp-Dl-Norleucine
CAS No.	31356-36-2
Molecular Formula	C12H15N3O6
Molecular Weight	297.27 g/mol
Synonyms	2,4-Dinitrophenyl-DL-norleucine; N-(2,4-Dinitrophenyl)-DL-norleucine; DL-Norleucine, N-(2,4-dinitrophenyl)-; DNP-DL-Norleucine; N-2,4-DNP-DL-Norleucine; (RS)-2-((2,4-Dinitrophenyl)amino)hexanoic acid; 2-(2,4-Dinitroanilino)hexanoic acid; DNP-Nle-OH
EINECS	Contact for details

Quality Control

Our n-2,4-Dnp-Dl-Norleucine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Melting Point	Specification available upon request
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.