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4-Bromo-2-Chlorobenzoic Acid CAS NO 59748-92-4


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CAS No.:59748-92-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Bromo-2-Chlorobenzoic Acid is a high-purity halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its dual halogen functionality, which provides distinct reactivity for selective cross-coupling and substitution reactions, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for developing active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in molecules requiring halogenated aromatic cores.
  • Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents.
  • Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing halogenated aromatic compounds used in electronic displays and organic light-emitting diodes.
  • Polymer Modifier: Incorporated as a monomer or additive to impart specific properties like flame retardancy or altered solubility to advanced polymers.
  • Cross-Coupling Reactions: Utilized in Suzuki, Heck, and Buchwald-Hartwig amination reactions due to the reactivity of the bromo and chloro substituents.
  • Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Product Name 4-Bromo-2-Chlorobenzoic Acid
CAS No. 59748-92-4
Molecular Formula C7H4BrClO2
Molecular Weight 235.46 g/mol
Synonyms 2-Chloro-4-bromobenzoic Acid; 4-Bromo-2-chlorobenzoic acid; Benzoic acid, 4-bromo-2-chloro-; 4-Bromo-o-chlorobenzoic Acid; 2-Chloro-4-bromobenzenecarboxylic Acid; NSC 403121; BRN 2090865
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Quality Control

Our 4-Bromo-2-Chlorobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. The compound may be light-sensitive; store away from direct light exposure.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥98.0%
Melting Point 158°C - 162°C
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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