Description

Dolichyl-Diphosphate-Di-n-Acetylchitobiose CAS NO 59694-82-5 is a key biochemical intermediate in the biosynthesis of N-linked glycoproteins. This compound matters as a critical donor substrate in the oligosaccharyltransferase (OST) complex reaction, essential for protein glycosylation pathways. It is primarily needed by researchers and manufacturers in the fields of glycobiology research, enzymology studies, and the development of biochemical tools for investigating congenital disorders of glycosylation (CDG).

Application

• Biochemical Research: As a high-purity substrate for studying the enzymatic mechanism of oligosaccharyltransferase (OST).
• Glycobiology Studies: Used in in vitro assays to reconstitute and analyze the early steps of N-linked glycan biosynthesis.
• Enzyme Kinetics & Inhibition: Serves as a standard or inhibitor in kinetic studies for drug discovery targeting glycosylation enzymes.
• Diagnostic Development: Potential use in developing assays for diagnosing congenital disorders of glycosylation (CDG).
• Pharmaceutical R&D: Intermediate in research focused on modulating protein glycosylation for therapeutic applications.
• Academic Research: A critical reagent for laboratories investigating cell biology, protein processing, and metabolic pathways.

Basic Information

Product Name	Dolichyl-Diphosphate-Di-n-Acetylchitobiose
CAS No.	59694-82-5
Molecular Formula	C₁₀₀H₁₆₈N₂O₂₀P₂ (Representative for Dol-PP-(GlcNAc)₂; exact formula varies with dolichyl chain length)
Molecular Weight	Contact for details (Variable based on dolichyl chain isomer)
Synonyms	Dolichyl Diphosphate Di-N-acetylchitobiose; Dol-PP-(GlcNAc)₂; Dolichyl Pyrophosphate N,N'-Diacetylchitobiose; Undecaprenyl Diphosphate Di-N-acetylchitobiose (bacterial analog); Chitobiosyldiphosphodolichol; Lipid-linked oligosaccharide precursor (LLO); DPP-DiNAcChitobiose; Donor substrate for oligosaccharyltransferase.
EINECS	Contact for details

Quality Control

Our Dolichyl-Diphosphate-Di-n-Acetylchitobiose is produced and handled under stringent conditions to ensure batch-to-batch consistency and high biochemical activity. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and structural confirmation via appropriate spectroscopic methods. Certificates of Analysis (COA) detailing identity, purity, and specific activity are available upon request to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in chloroform/methanol/water mixtures
Specific Activity (if applicable)	Contact for details
Water Content (Karl Fischer)	< 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.