Description

4-(Tetrahydropyran-2-Yloxy)-1-Butene is a versatile protected hydroxyl intermediate, specifically a tetrahydropyranyl (THP) ether derivative of 3-buten-1-ol. This compound is valued for its role as a key building block in organic synthesis, where the THP group serves as a robust protecting group for alcohols under a wide range of reaction conditions. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in multi-step syntheses for the production of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development and manufacturing of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Serves as a protected synthon for creating complex fragrance compounds, flavors, and specialty polymers.
• Academic & Industrial Research: A valuable reagent in medicinal chemistry and methodology development for exploring new synthetic pathways.
• Peptide & Natural Product Synthesis: Employed to protect hydroxyl functionalities during the synthesis of complex natural products and modified peptides.

Basic Information

Product Name	4-(Tetrahydropyran-2-Yloxy)-1-Butene
CAS No.	59574-65-1
Molecular Formula	C9H16O2
Molecular Weight	156.22 g/mol
Synonyms	3-Buten-1-ol, tetrahydropyranyl ether; 1-Butene, 4-(tetrahydro-2H-pyran-2-yloxy)-; 4-(THP-Oxy)-1-butene; 3-Butenyl tetrahydropyranyl ether; THP ether of 3-buten-1-ol; 2-(3-Butenyloxy)tetrahydropyran; 4-(Oxan-2-yloxy)but-1-ene
EINECS	Contact for details

Quality Control

Our 4-(Tetrahydropyran-2-Yloxy)-1-Butene is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee supply reliability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.