Description

4-Bromo-2-Phenylquinazoline is a high-value brominated quinazoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in its versatile halogenated aromatic structure, which enables precise molecular construction for complex target molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to build novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential kinase inhibitors, anticancer agents, and other biologically active quinazoline-based compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the quinazoline scaffold's bioactivity.
• Material Science Precursor: Serves as a monomer or functional unit in the creation of organic semiconductors, liquid crystals, and advanced polymers.
• Chemical Synthesis Reagent: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a versatile electrophile in nucleophilic aromatic substitution.
• Academic & R&D Laboratories: Fundamental research compound for studying heterocyclic chemistry, reaction mechanisms, and structure-activity relationships (SAR).

Basic Information

Product Name	4-Bromo-2-Phenylquinazoline
CAS No.	59456-01-8
Molecular Formula	C₁₄H₉BrN₂
Molecular Weight	285.14 g/mol
Synonyms	2-Phenyl-4-bromoquinazoline; 4-Bromo-2-phenyl-quinazoline; Quinazoline, 4-bromo-2-phenyl-; 4-Brom-2-phenylchinazolin (German); 4-ブロモ-2-フェニルキナゾリン (Japanese); 4-溴-2-苯基喹唑啉 (Chinese); BR-PQZ
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Phenylquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates for GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.