Description

3-Bromo-4-Methylquinoline is a versatile brominated quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique halogenated structure, which facilitates selective cross-coupling reactions and functional group transformations essential for building complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in the development of antimalarial, antibacterial, and kinase inhibitor compounds.
• Agrochemical Research: Used in the creation of novel fungicides, herbicides, and pesticides, leveraging the quinoline scaffold's bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to introduce the quinoline moiety into more complex molecules.
• Ligand Synthesis: Useful for preparing nitrogen-containing ligands for catalysis and coordination chemistry.

Basic Information

Product Name	3-Bromo-4-Methylquinoline
CAS No.	59280-69-2
Molecular Formula	C10H8BrN
Molecular Weight	222.08 g/mol
Synonyms	4-Methyl-3-bromoquinoline; 3-Bromo-4-methylquinoline; Quinoline, 3-bromo-4-methyl-; 59280-69-2
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Methylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.