Description

Deoxycholic Acid 3-o-β-D-Glucuronide Disodium Salt is a high-purity conjugated bile acid derivative, a critical biochemical reagent and pharmaceutical intermediate. This compound is valued for its role as a specific metabolite and reference standard in advanced research and development. It is essential for laboratories and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors requiring precise biochemical tools for metabolic studies, enzyme assays, and quality control.

Application

• Biochemical Research: Used as a key metabolite and substrate in studies of bile acid metabolism, liver function, and enterohepatic circulation.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the analytical method development and validation of related drug substances and impurities.
• Diagnostic Reagent Manufacturing: Employed in the formulation of enzymatic assay kits for the clinical measurement of bile acids and liver markers.
• Enzymology Studies: Acts as a specific substrate for glucuronidase and other hydrolytic enzymes in kinetic and inhibition assays.
• Metabolite Identification: A crucial standard in LC-MS and HPLC analyses for the identification and quantification of deoxycholic acid conjugates in biological samples.
• Academic & Contract Research: Provides a well-defined chemical tool for universities and CROs conducting research in gastroenterology, hepatology, and metabolic diseases.

Basic Information

Product Name	Deoxycholic Acid 3-o-β-D-Glucuronide Disodium Salt
CAS No.	59274-67-8
Molecular Formula	C26H39Na2O10
Molecular Weight	556.57 g/mol
Synonyms	3α,12α-Dihydroxy-5β-cholan-24-oic Acid 3-β-D-Glucopyranosiduronic Acid Disodium Salt; Deoxycholic Acid 3-Glucuronide Disodium Salt; Sodium Deoxycholate 3-Glucuronide; DCA-3G Na2; 3-Glucuronodeoxycholic Acid Disodium Salt; Disodium 3-[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]-β-D-glucopyranosiduronate
EINECS	Contact for details

Quality Control

Our Deoxycholic Acid 3-o-β-D-Glucuronide Disodium Salt is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture. For long-term storage, consider desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.