Description

3-Phenylspiro[Isobenzofuran-1(3H),4'-Piperidine] is a high-purity, advanced pharmaceutical intermediate with a complex spirocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) drugs and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential neuroactive compounds and receptor modulators.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing libraries of novel chemical entities in drug discovery programs.
• Organic Synthesis: Serves as a specialized building block for constructing complex spirocyclic and heterocyclic frameworks.
• Biochemical Research: Employed in the study of biological pathways and as a tool compound for target validation.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of Active Pharmaceutical Ingredients (APIs) under cGMP.

Basic Information

Product Name	3-Phenylspiro[Isobenzofuran-1(3H),4'-Piperidine]
CAS No.	59142-94-8
Molecular Formula	C19H19NO
Molecular Weight	277.36 g/mol
Synonyms	3-Phenyl-1,3-dihydrospiro[isobenzofuran-1,4'-piperidine]; 3-Phenylspiro[isobenzofuran-1(3H),4'-piperidine]; Spiro[isobenzofuran-1(3H),4'-piperidine], 3-phenyl-; 59142-94-8; 3-Phenyl-1-azaspiro[4.5]decan-1-one (tautomeric form); 3-Phenylspiro(2-benzofuran-1,4'-piperidine); 3-Phenyl-1,3-dihydro-1,4'-bipiperidine-1'-spiro-2'-benzofuran
EINECS	Contact for details

Quality Control

Our 3-Phenylspiro[Isobenzofuran-1(3H),4'-Piperidine] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can supply material compliant with research-grade standards and support development toward cGMP-grade production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.