Description

3-Bromo-4-Hydroxy-2-(Trifluoromethyl)Quinoline is a high-value, multi-functional heterocyclic building block characterized by its bromo, hydroxy, and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antimicrobial research.
• Agrochemical Synthesis: Building block for advanced herbicides, fungicides, and insecticides leveraging the trifluoromethyl group's lipophilicity.
• Material Science Research: Precursor for functionalized quinoline-based ligands, polymers, or organic electronic materials.
• Chemical Biology Probes: Used in medicinal chemistry to create tool compounds for target validation and mechanism-of-action studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific molecules at various scales.

Basic Information

Product Name	3-Bromo-4-Hydroxy-2-(Trifluoromethyl)Quinoline
CAS No.	59108-47-3
Molecular Formula	C₁₀H₅BrF₃NO
Molecular Weight	292.06 g/mol
Synonyms	3-Bromo-4-hydroxy-2-(trifluoromethyl)quinoline; 4-Hydroxy-3-bromo-2-trifluoromethylquinoline; 2-(Trifluoromethyl)-3-bromo-4-quinolinol; Quinoline, 3-bromo-4-hydroxy-2-(trifluoromethyl)-; 59108-47-3; 3-Bromo-4-hydroxy-2-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Hydroxy-2-(Trifluoromethyl)Quinoline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided and available upon request, supporting compliance with cGMP and ISO 9001 standards for reliable integration into your supply chain.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.