Description

8-Bromo-2-(trifluoromethyl)quinolin-4-ol is a versatile and highly functionalized quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both bromine and trifluoromethyl substituents, makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients, as well as by manufacturers of specialty chemicals and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for targets in oncology, neurology, and infectious diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Acts as a versatile scaffold for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitutions, enabling rapid diversification.
• Ligand and Catalyst Development: Utilized to synthesize novel chelating ligands for metal complexes used in catalysis and sensing applications.
• Fluorescent Probe Synthesis: The quinoline structure is ideal for creating dyes and molecular probes for biochemical and diagnostic applications.

Basic Information

Product Name	8-Bromo-2-(trifluoromethyl)quinolin-4-ol
CAS No.	59108-43-9
Molecular Formula	C10H5BrF3NO
Molecular Weight	292.06 g/mol
Synonyms	4-Hydroxy-8-bromo-2-(trifluoromethyl)quinoline; 8-Bromo-2-trifluoromethyl-4-quinolinol; 8-Bromo-2-(trifluoromethyl)-4-hydroxyquinoline; 8-Bromo-2-(trifluoromethyl)-4-quinolinol; 2-(Trifluoromethyl)-8-bromoquinolin-4-ol; 59108-43-9; Quinolin-4-ol, 8-bromo-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 8-Bromo-2-(trifluoromethyl)quinolin-4-ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.