Description

5-Chloro-8-Methyl-2-(Trifluoromethyl)Quinolin-4-Ol is a high-value, multi-functional quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular structure, featuring chloro, methyl, and trifluoromethyl substituents, makes it an essential building block for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Research: Used as a core scaffold for developing new generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline moiety.
• Material Science: Serves as a building block for advanced organic electronic materials, such as charge-transport layers or light-emitting components, due to its conjugated system.
• Chemical Synthesis: Versatile intermediate for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.

Basic Information

Product Name	5-Chloro-8-Methyl-2-(Trifluoromethyl)Quinolin-4-Ol
CAS No.	59108-09-7
Molecular Formula	C₁₁H₇ClF₃NO
Molecular Weight	261.63 g/mol
Synonyms	4-Hydroxy-5-chloro-8-methyl-2-(trifluoromethyl)quinoline; 5-Chloro-8-methyl-2-(trifluoromethyl)-4-quinolinol; 5-Chloro-8-methyl-2-trifluoromethylquinolin-4-ol; 4-Quinolinol, 5-chloro-8-methyl-2-(trifluoromethyl)-; 59108-09-7; 5-Chloro-8-methyl-2-(trifluoromethyl)-4-hydroxyquinoline
EINECS	Contact for details

Quality Control

Our 5-Chloro-8-Methyl-2-(Trifluoromethyl)Quinolin-4-Ol is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, with each shipment. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are essential for regulatory submissions and quality assurance in critical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.