Description

1-Bromo-6-Fluoronaphthalene is a high-purity halogenated naphthalene derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of bromine and fluorine atoms on the naphthalene ring, enabling precise functionalization and tuning of electronic properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a fluorinated naphthalene core.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides where the halogenated structure imparts specific biological activity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and host molecules in OLED displays and lighting.
• Liquid Crystal Materials: Employed in the synthesis of fluorinated components for liquid crystal mixtures used in displays.
• Polymer & Material Science: Acts as a monomer or functionalizing agent for creating specialty polymers with enhanced thermal stability or specific optical properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating novel fluorinated aromatic compounds in academic and industrial R&D.

Basic Information

Product Name	1-Bromo-6-Fluoronaphthalene
CAS No.	59079-74-2
Molecular Formula	C₁₀H₆BrF
Molecular Weight	225.06 g/mol
Synonyms	6-Fluoro-1-bromonaphthalene; 1-Bromo-6-fluoronaphthalene; Naphthalene, 1-bromo-6-fluoro-; 6-Fluoronaphthalen-1-yl bromide; 1-Brom-6-fluornaphthalin (German); 1-ブロモ-6-フルオロナフタレン (Japanese); Bromofluoronaphthalene
EINECS	Contact for details

Quality Control

Our 1-Bromo-6-Fluoronaphthalene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.