Description

Syn-Benzo(A)Pyrenediolepoxide CAS NO 58917-91-2 is a high-purity, synthetically produced metabolite of Benzo[a]pyrene, a well-studied polycyclic aromatic hydrocarbon (PAH). This compound is of critical importance as a reference standard and a key reactive intermediate in toxicological and metabolic research. It is primarily required by analytical laboratories, environmental testing facilities, and research institutions focused on studying carcinogenesis, DNA adduct formation, and the metabolic pathways of PAHs.

Application

• Analytical Reference Standard: Used for the calibration and validation of analytical methods (e.g., HPLC, GC-MS) in environmental and biological monitoring.
• Toxicology Research: Serves as a crucial reagent in studies investigating the mechanisms of chemical carcinogenesis and mutagenicity.
• Metabolic Pathway Studies: Employed to trace and understand the biotransformation pathways of Benzo[a]pyrene in biological systems.
• DNA Adduct Research: Used as a model compound to study the formation and repair of DNA adducts, which are critical events in cancer development.
• Biomarker Development: Acts as a standard in the development of assays to detect PAH exposure and related biological effects in occupational and environmental health.
• Pharmaceutical & Chemical Safety Testing: Utilized in safety assessment protocols to evaluate the potential genotoxic effects of new chemical entities.

Basic Information

Product Name	Syn-Benzo(A)Pyrenediolepoxide
CAS No.	58917-91-2
Molecular Formula	C₂₀H₁₂O₃
Molecular Weight	300.31 g/mol
Synonyms	Benzo[a]pyrene-7,8-diol-9,10-epoxide; BPDE; (+)-anti-Benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide; 7,8-Dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene; anti-BPDE; Benzo[a]pyrene diolepoxide I; B[a]PDE; 7,8-Dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene
EINECS	Contact for details

Quality Control

Our Syn-Benzo(A)Pyrenediolepoxide is manufactured under strict quality-controlled conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. Allow the sealed container to reach room temperature before opening to prevent moisture condensation. Keep away from oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.