Description

1-(4-Fluorophenyl)-2-(1H-1,2,4-Triazole-1-Yl)Ethanone CAS NO 58905-21-8 is a high-purity, specialized organic compound featuring a unique molecular scaffold combining a fluorinated phenyl ring with a 1,2,4-triazole moiety. This structure makes it a critical intermediate for synthesizing advanced active pharmaceutical ingredients (APIs) and agrochemicals, where its precise chemical architecture is essential for imparting specific biological activity. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of antifungal and other bioactive molecules, particularly those targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and production of advanced fungicides and herbicides, leveraging the triazole group's known bioactivity.
• Chemical Research & Development: Serves as a versatile precursor for creating novel chemical libraries in medicinal chemistry and material science.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the multi-step synthesis of final drug substances requiring a fluorinated triazole component.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	1-(4-Fluorophenyl)-2-(1H-1,2,4-Triazole-1-Yl)Ethanone
CAS No.	58905-21-8
Molecular Formula	C10H8FN3O
Molecular Weight	205.19 g/mol
Synonyms	2-(1H-1,2,4-Triazol-1-yl)-1-(4-fluorophenyl)ethanone; 1-(4-Fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-one; 4-Fluoro-α-(1H-1,2,4-triazol-1-yl)acetophenone; 58905-21-8; FC-TAZ; Fluorophenyl triazolyl ethanone
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-2-(1H-1,2,4-Triazole-1-Yl)Ethanone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting all test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.