Description

6-(2-Bromoacetyl)-2H-Benzo[B][1,4]Oxazin-3(4H)-One is a versatile and highly functionalized heterocyclic building block. This compound is valued for its reactive bromoacetyl moiety, which makes it a critical intermediate in the synthesis of more complex molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in the synthesis of compounds with benzoxazinone scaffolds which exhibit a range of biological activities.
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its reactive site for structural diversification.
• Chemical Biology & Proteomics: Serves as a potential building block for activity-based probes (ABPs) or affinity tags due to its electrophilic carbonyl group.
• Material Science: Employed in the synthesis of specialty polymers and organic electronic materials where the benzoxazinone unit can impart specific properties.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	6-(2-Bromoacetyl)-2H-Benzo[B][1,4]Oxazin-3(4H)-One
CAS No.	58819-97-9
Molecular Formula	C10H8BrNO3
Molecular Weight	270.08 g/mol
Synonyms	6-(2-Bromoacetyl)-3,4-dihydro-2H-1,4-benzoxazin-3-one; 2-Bromo-1-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)ethanone; 6-(Bromoacetyl)-2H-1,4-benzoxazin-3(4H)-one; 6-(2-Bromoacetyl)-2H-benzo[b][1,4]oxazin-3(4H)-one; 6-(Bromoacetyl)-3,4-dihydro-2H-1,4-benzoxazin-3-one; 1-(3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-2-bromoethan-1-one
EINECS	Contact for details

Quality Control

Our 6-(2-Bromoacetyl)-2H-Benzo[B][1,4]Oxazin-3(4H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under inert atmosphere when possible and opened with minimal exposure to ambient humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.