Description

H-4-Nitro-Phe-Oet Hcl is a protected amino acid derivative, specifically the ethyl ester hydrochloride salt of 4-Nitro-L-phenylalanine. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, particularly for the pharmaceutical and biotechnology sectors. It is essential for researchers and manufacturers developing peptide-based therapeutics, enzyme inhibitors, and other bioactive molecules where precise stereochemistry and functional group manipulation are required.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and peptide drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate the 4-nitro-phenylalanine moiety into peptide chains.
• Proteomics & Biochemical Research: Serves as a building block for creating custom peptides, enzyme substrates, and molecular probes in life science research.
• Agrochemical Development: Potential intermediate in the design and synthesis of advanced crop protection agents and specialty agrochemicals.
• Material Science: Can be utilized in the development of specialty polymers and functional materials that require aromatic amino acid derivatives.

Basic Information

Product Name	H-4-Nitro-Phe-Oet Hcl
CAS No.	58816-66-3
Molecular Formula	C11H14N2O4•HCl
Molecular Weight	274.70 g/mol
Synonyms	L-4-Nitro-phenylalanine ethyl ester hydrochloride; (S)-2-Amino-3-(4-nitrophenyl)propanoic acid ethyl ester hydrochloride; 4-Nitro-L-phenylalanine ethyl ester HCl; H-Phe(4-NO2)-OEt•HCl; Ethyl (2S)-2-amino-3-(4-nitrophenyl)propanoate hydrochloride; 4-Nitro-L-Phe-OEt•HCl; Fmoc-Phe(4-NO2)-OH precursor; N-α-H-4-Nitrophenylalanine ethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our H-4-Nitro-Phe-Oet Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.