Description

p-Aminophenyl-1-Thio-β-D-Glucopyranos Ide is a specialized thioglycoside derivative, a key synthetic intermediate in organic and medicinal chemistry. Its core value lies in its unique structure, combining a reactive aniline moiety with a protected sugar unit, enabling the synthesis of complex bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing glycosidase inhibitors, targeted drug conjugates, and novel carbohydrate-based probes.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of glycosidase inhibitors and other carbohydrate-based therapeutics.
• Bioconjugation Chemistry: Used in the development of antibody-drug conjugates (ADCs) and other targeted delivery systems via its reactive thio and amino groups.
• Glycobiology Research: Serves as a precursor for synthesizing neoglycoconjugates, glycoclusters, and other tools to study carbohydrate-protein interactions.
• Chemical Probe Development: Utilized to create activity-based probes (ABPs) for labeling and studying glycosidases in biological systems.
• Agrochemical Synthesis: Potential intermediate in the development of novel, sugar-based plant protection agents or growth regulators.
• Material Science: Can be incorporated into the design of functionalized polymers or surfaces with specific carbohydrate recognition properties.

Basic Information

Item	Details
Product Name	p-Aminophenyl-1-Thio-β-D-Glucopyranos Ide
CAS No.	58737-22-7
Molecular Formula	C12H17NO5S
Molecular Weight	287.33 g/mol
Synonyms	4-Aminophenyl 1-Thio-β-D-glucopyranoside; p-Aminophenyl β-D-Thioglucopyranoside; 1-Thio-β-D-glucopyranosiduronic acid, 4-aminophenyl; 4-Aminophenyl thioglucoside; APTG; p-Aminophenyl thioglucopyranoside; 4-Aminophenyl 1-Thio-β-D-glucoside
EINECS	Contact for details

Quality Control

Our p-Aminophenyl-1-Thio-β-D-Glucopyranos Ide is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We employ advanced analytical techniques, including HPLC and NMR, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.