Description

3,4-Dibromo-1,8-Naphthyridine is a high-purity halogenated naphthyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique bromine substitution pattern, which provides reactive handles for cross-coupling and functionalization reactions, enabling the construction of complex heterocyclic architectures. This compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and materials science, particularly for creating novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or possessing antiviral or anticancer properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the naphthyridine core for bioactivity.
• Material Science Precursor: Employed in the creation of organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional organic materials.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand Synthesis: Utilized to prepare complex chelating ligands for catalysis or metal ion sensing applications.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.

Basic Information

Product Name	3,4-Dibromo-1,8-Naphthyridine
CAS No.	58680-43-6
Molecular Formula	C8H4Br2N2
Molecular Weight	287.94 g/mol
Synonyms	1,8-Naphthyridine, 3,4-dibromo-; 3,4-Dibromo-1,8-naphthyridine; 3,4-Dibromonaphthyridine; Dibromonaphthyridine; 58680-43-6; 1,8-Diazanaphthalene, 3,4-dibromo-; 3,4-Dibromo-1,8-diazanaphthalene
EINECS	Contact for details

Quality Control

Our 3,4-Dibromo-1,8-Naphthyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.