Description

4-Bromo-1,7-Naphthyridine is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its bromine substituent, which serves as a reactive handle for cross-coupling reactions, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a building block for creating organic semiconductors, ligands for catalysts, and photoactive materials.
• Cross-Coupling Reactions: The bromine atom is ideal for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form carbon-carbon and carbon-nitrogen bonds.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target identification.
• Academic & R&D: A fundamental reagent for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	4-Bromo-1,7-Naphthyridine
CAS No.	58680-40-3
Molecular Formula	C8H5BrN2
Molecular Weight	209.04 g/mol
Synonyms	4-Bromo-1,7-naphthyridine; 1,7-Naphthyridine, 4-bromo-; 4-Bromonaphthyridine; 4-Bromo-1,7-diazanaphthalene; 4-Bromopyrido[3,2-c]pyridine; 4-Bromo-1,7-naphthyridine (CAS 58680-40-3); 4-Br-1,7-Naph
EINECS	Contact for details

Quality Control

Our 4-Bromo-1,7-Naphthyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with your specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.