Description

4(3H)-Quinazolinone, 2-Amino-6-(Bromomethyl)- is a high-value brominated quinazolinone derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino group and a reactive bromomethyl substituent, makes it an essential intermediate for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where precise molecular modification is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or possessing anticancer activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the quinazolinone scaffold.
• Chemical Biology Probe Synthesis: Serves as a versatile handle for creating molecular probes to study biological pathways and protein functions.
• Material Science Research: Building block for creating novel organic electronic materials or metal-organic frameworks (MOFs) with specialized properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	4(3H)-Quinazolinone, 2-Amino-6-(Bromomethyl)-
CAS No.	58677-08-0
Molecular Formula	C9H8BrN3O
Molecular Weight	254.09 g/mol
Synonyms	2-Amino-6-(bromomethyl)-4(3H)-quinazolinone; 6-(Bromomethyl)-2-amino-3H-quinazolin-4-one; 2-Amino-6-bromomethylquinazolin-4(3H)-one; 2-Amino-6-(bromomethyl)-3H-quinazolin-4-one; 6-Bromomethyl-2-amino-4(3H)-quinazolinone; Quinazolinone, 2-amino-6-(bromomethyl)-; 58677-08-0
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-6-(Bromomethyl)-4(3H)-Quinazolinone is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), and impurity profiles is supplied with each shipment to guarantee traceability and consistency for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.