Description

tert-Butyl 3-Nitrobenzoate is a high-purity organic intermediate characterized by its nitro-substituted benzoate ester structure. This compound is valued for its role as a versatile building block in advanced organic synthesis, enabling the introduction of both the tert-butyl ester protecting group and a nitro functional handle. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a protected carboxylic acid moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the nitro group serves as a critical synthetic intermediate.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis and metal complexation.
• Polymer Chemistry: Acts as a monomer or functionalization agent in the production of specialty polymers and advanced materials.
• Chemical Research: Serves as a standard or starting material in academic and industrial laboratories for methodological development and scale-up studies.
• Dye and Pigment Intermediates: Utilized in the synthesis of nitro-aromatic compounds that are further processed into colorants.

Basic Information

Product Name	tert-Butyl 3-Nitrobenzoate
CAS No.	58656-99-8
Molecular Formula	C11H13NO4
Molecular Weight	223.23 g/mol
Synonyms	3-Nitrobenzoic Acid tert-Butyl Ester; Benzoic Acid, 3-Nitro-, 1,1-Dimethylethyl Ester; tert-Butyl m-Nitrobenzoate; 1,1-Dimethylethyl 3-Nitrobenzoate; m-Nitrobenzoic Acid tert-Butyl Ester; 3-Nitro-benzoic Acid tert-butyl Ester; (1,1-Dimethylethyl) 3-Nitrobenzoate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Nitrobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment supports applications requiring reliable and traceable raw materials for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.