Description

5,6,7,8-Tetrahydroquinolin-4(1H)-One is a versatile heterocyclic building block and key synthetic intermediate with significant commercial value. Its partially saturated quinoline core structure makes it a crucial precursor in the synthesis of complex pharmaceutical compounds and advanced organic materials. This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, light-emitting materials, and advanced polymers.
• Chemical Research & Development: A valuable starting material for academic and industrial research into new heterocyclic compounds and reaction methodologies.
• Dye and Pigment Intermediate: Used in the synthesis of specialized colorants and photographic chemicals.

Basic Information

Item	Details
Product Name	5,6,7,8-Tetrahydroquinolin-4(1H)-One
CAS No.	58596-31-9
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	4-Hydroxy-5,6,7,8-tetrahydroquinoline; 4-Oxo-1,4,5,6,7,8-hexahydroquinoline; 5,6,7,8-Tetrahydro-4(1H)-quinolinone; 1,2,3,4-Tetrahydro-4-oxoquinoline; 4-Quinolinone, 1,2,3,4-tetrahydro-; Tetrahydro-4-quinolone
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydroquinolin-4(1H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity, consistency, and traceability. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.