Description

1-tert-Butyl-3-Nitro-4-Chlorobenzene is a high-purity, synthetically valuable halogenated nitroaromatic compound. This chemical serves as a critical advanced intermediate in the synthesis of complex organic molecules, prized for its unique substitution pattern that enables selective chemical transformations. It is primarily utilized by pharmaceutical, agrochemical, and specialty chemical manufacturers for research and development as well as commercial-scale production processes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a substituted benzene core.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the tert-butyl and nitro groups impart specific biological activity.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and other complex colorants, leveraging the nitro group for chromophore development.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers as a functional monomer.
• Cross-Coupling Reactions: The chlorine atom makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations.
• Chemical Research & Development: A versatile reagent for exploring novel organic transformations and synthesizing libraries of compounds for screening.

Basic Information

Product Name	1-tert-Butyl-3-Nitro-4-Chlorobenzene
CAS No.	58574-05-3
Molecular Formula	C10H12ClNO2
Molecular Weight	213.66 g/mol
Synonyms	4-Chloro-1-tert-butyl-3-nitrobenzene; 4-Chloro-3-nitro-tert-butylbenzene; 1-Chloro-2-tert-butyl-4-nitrobenzene; 2-tert-Butyl-4-chloro-1-nitrobenzene; 3-Nitro-4-chloro-tert-butylbenzene; 4-Chloro-3-nitro-1-(1,1-dimethylethyl)benzene; Benzene, 1-(1,1-dimethylethyl)-4-chloro-3-nitro-; 1-tert-Butyl-4-chloro-3-nitrobenzene
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl-3-Nitro-4-Chlorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity, consistency, and traceability. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for use as a pharmaceutical and agrochemical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.