Description

(1S,2S)-Bis(4-Methoxyphenyl)-1,2-Ethanediamine is a high-purity chiral diamine building block of significant importance in asymmetric synthesis. This compound matters because its rigid, enantiomerically pure structure serves as a key ligand and precursor for catalysts used in creating complex pharmaceutical intermediates. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A critical chiral scaffold for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Asymmetric Catalyst Ligand: Used as a precursor or direct ligand in transition metal catalysis (e.g., for hydrogenation or C-C bond formation) to induce high enantioselectivity.
• Agrochemical Synthesis: Employed in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Building Block: Serves as a versatile starting material for synthesizing complex molecules in material science and specialty chemistry.
• Resolution Agent: Can be utilized for the chiral resolution of racemic mixtures of carboxylic acids or other compounds.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with specific optical or mechanical properties.

Basic Information

Item	Details
Product Name	(1S,2S)-Bis(4-Methoxyphenyl)-1,2-Ethanediamine
CAS No.	58520-04-0
Molecular Formula	C₁₆H₂₀N₂O₂
Molecular Weight	272.34 g/mol
Synonyms	(1S,2S)-(-)-1,2-Bis(4-methoxyphenyl)ethylenediamine; (S,S)-(-)-1,2-Bis(4-methoxyphenyl)ethylenediamine; (1S,2S)-1,2-Di(4-methoxyphenyl)ethane-1,2-diamine; (S,S)-DIPAMP diamine precursor; (S,S)-Bis(4-methoxyphenyl)ethylenediamine; (1S,2S)-Bis(p-methoxyphenyl)ethylenediamine; (S,S)-Bis(4-anisyl)ethylenediamine; Jacobsen's Ligand precursor
EINECS	Contact for details

Quality Control

Our (1S,2S)-Bis(4-Methoxyphenyl)-1,2-Ethanediamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >98%), enantiomeric excess (ee), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect purity and stability. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.